10.3390/molecules26030752 63 MainaS.MisinzoG.BakariG.KimH
This happens because the tool floors decimal doses to ensure that full doses only are counted
Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)
For many users, this model speeds appropriate care and reduces unnecessary travel to clinics or emergency rooms
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