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Data in panel b,c,i,k,m-p were analyzed using Students two-tailed, two-sided ttest

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PLoS One 6 , e23462 (2011)

An equivalent amount of protein from each animal was mixed with 4 sample buffer with or without 2-mercaptoethanol, then separated by SDSpolyacrylamide gel electrophoresis, and transferred electrophoretically to a PVDF membrane (Merck Millipore)

Our studies identify a histone acetylation pathway promoted by KG production that is indispensable for HR proficiency and corresponding resistance to DNA-damaging agents