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B vitamins are necessary for the proper functioning of the methylation cycle, DNA synthesis, repair and maintenance of phospholipids and generally essential for healthy skin, muscles, brain, and nerve functionality.3 The individual functions are described below but more often than not they work together to achieve the required effect

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The most frequently reported symptoms included: Nausea (the most common, with rates varying by dose readers should refer to the published trial data and supplementary tables for dose-specific figures) Vomiting Diarrhoea Constipation Upper abdominal pain or discomfort Decreased appetite These effects are largely attributable to the drug's action on GLP-1 receptors in the gastrointestinal tract, which slow gastric motility and alter gut hormone signalling