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Enrollees in the clinical trial receiving Retatrutide also experienced improvements in blood pressure and lipid profile

Some therapeutic benefit has been demonstrated in patients with mild forms CPT-2 deficiency with the use of the fibrate drug, bezafibrate

In other words, statin intolerance is not only the lack of statin treatment due to clinical or biochemical symptoms (so-called complete intolerance, which affects only 35% of patients), but also the phenomenon of underdosage or the use of a statin too weak in relation to the cardiovascular risk [8]

Ethics declarations Ethics Approval and Consent to Participate All experiments were conducted by the Ethical Principles in Animal Experimentation and were accepted by the Ethics Committee on the Use of Animals of the Aggeu Magalhes Institute (CEUA 135/2018-IAM)

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