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This phenomenon is thought to result from compensatory mechanisms, such as increased SGLT1 activity and upregulation of SGLT2 expression
Clinical observations suggest that long-term use of LDL-apheresis in patients with severe HoFH contributes to regression and stabilisation of atherosclerotic plaques, improves cardiovascular prognosis, and reduces xanthomata of the skin and tendons [260]
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In the placebo groups, 20 patients developed UTIs
Individuals should seek medical attention if they have prolonged nausea or vomiting, or an inability to take in fluids
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