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Retatrutide has the most promising metabolic profile but the least long-term cardiac data

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Examples include: Dilantin (phenytoin) Norvir (ritonavir) and other medicines that contain ritonavir, such as Kaletra Phenobarbital Sustiva (efavirenz) and other medicines that contain efavirenz Tegretol (carbamazepine) Drugs that are metabolized by an enzyme called CYP2D6 Bupropion inhibits an enzyme called CYP2D6, which could lead to increased levels in the body of certain medications (examples are listed below), referred to as CYP2D6 substrates