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Using an extensively validated monoclonal antibody, one landmark study mapped the receptor to beta cells in the pancreas, the myocytes of the sinoatrial node in the heart, and the smooth muscle of arteries and arterioles in the kidney and lung

*Study based on adults with a starting weight of about 232 lbs

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Future studies should investigate the downstream GLP-1R signaling pathways and enteroendocrine regulatory influenced by Akk11, as well as the long-term durability of these effects and the feasibility of clinical trials