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Im a board-certified gastroenterologist with 20+ years of professional experience and 30 + years of personal gut and rectal challenges
The grey market fills that gap with cheaper, more accessible, and far more dangerous products
The increased risk of DKA in the SGLT2i group, and the associated hospitalisation, was not great enough to offset the increased rate of hospitalisation of any cause in the GLP-1 RA group
Finally, they have a skin-restricted TYK2/JAK1/JAK2 inhibitor as a topical agent for dermatological diseases (HL300) Outside of this, they have HL500 which is a brain-penetrant LRRK2 inhibitor being developed for Parkinsons, and HL400, a brain-penetrant NLRP3 inhibitor designed using molecular glue technology
The connection between mold exposure and Mast Cell Activation Syndrome (MCAS) is one of the most significant discoveries in environmental medicine
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