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The cardio-ankle vascular index (CAVI), a prognostic marker for cardiovascular events, declined by approximately 0.2 points bilaterally, reflecting improved arterial elasticity

ACS Chem Neurosic 10 (2), 777782

[7] So the honest one-line summary is that both build on GLP-1 but recruit a different second pathway amylin for CagriSema, GIP for tirzepatide and there is a further structural difference underneath that: CagriSema achieves its dual action with two separate peptides, while tirzepatide achieves its dual action with one

Those with certain conditions: Milk thistle can have estrogenic effects, which may worsen hormone-sensitive conditions, including some types of breast cancer

Patients with elevated baseline inflammatory markers (CRP, IL-6) or copper metabolism disorders may face higher risk of adverse reactions