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(Lond) 40 (8), 13101319

In one study, liraglutide and semaglutide were reported to mitigate the development of plaque lesions by changing the inflammatory pathway in a mouse model of AS (124)

However, the evidence base for three times weekly sublingual dosing is thin compared to the robust clinical trial data supporting daily oral and weekly injectable protocols

The work so far has been done in labs or with animals and is still in early stages

In a 12-month study of 339 Second Nature members published in JMIR Formative Research, participants on tirzepatide lost an average of 22.1% of their body weight, and those on semaglutide lost 17.1% 11