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In brief, local wounding results in breakdown of cells and release of fatty acids, and at the same time, cleavage of the octadecapeptide systemin is initiated from prosystemin to stimulate jasmonic acid biosynthesis with various jasmonic acid conjugates

Vibration controlled transient elastography (VCTE) is most commonly used methods to assess for fibrosis, with liver stiffness measurements less than 8 kPa used to rule out advanced fibrosis

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Subsequently, Matsuzawa et al

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