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The presence of high concentrations of tyrosine in the locus coeruleus and the substantia nigra leads to increased melanin synthesis which confers on these brain regions a dark bluish coloration observable in brain sections

(2020) characterized the ternary copper complex formed between GHK, copper(II), and cis-urocanic acid (a UV-absorbing compound in skin), demonstrating a potential mechanism for GHK-Cu to function as a solar photoprotectant while maintaining its copper-delivery function