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J., Ramirez, M., & Block, J

If that methionine residue plays a role in receptor binding or biological activity, oxidation can reduce or eliminate the peptide effect entirely

Diminished GLP-1 leads to attenuated insulin release leading to type-2 diabetes

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In these contexts, decision making becomes shaped by anecdotal and influencer-driven information rather than clinical evidence. This in turn posed a problem for GPs, with many users either not disclosing their use of peptides, or not identifying themselves as substance users