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Acetyl L-Carnitine's overall importance is underscored by its role in the brain where it can bypass the blood-brain barrier to deliver its benefits directly to the brain

Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans, Stier H., Vos E., Kenley D., Journal (Journal of Endocrinology and Metabolism, Volume 3, Issues 12, 2013, Pages 715)

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but declining GHK production means less signal and less repair with each passing decade