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Journal Internal Medicine 28, 916

We observed a significant upregulation in IL-10 levels and significant downregulation of TNF-, IL-6, and IL-1 in GGC-treated cells, suggestive of the beneficial effects of GGC against oligomeric A 40 -induced neuroinflammatory response

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Biomolecules 9:232

For example, ascorbate is required for opening the ring structure of 1-aminocyclopropane-1-carboxylic acid (ACC) by supplying the electron to the active site of ACC oxidase, which catalyses the last step of ethylene biosynthesis (Smirnoff, 2018)