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They remain relevant as inexpensive oral alternatives for patients refusing injection or with incretin contraindications

Due to this extended activity, side effects can last several days, which is why these medications are typically started at low doses and gradually titrated to the desired level

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Despite the very low absolute risk for ischemic optic neuropathy, the rapidly expanding use of GLP-1 receptor agonists in patients with and without type 2 diabetes increases the clinical and public health importance of any potential association, conclude the authors

For nausea specifically, I recommend keeping electrolytes by your bed to drink first thing in the morning