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How the compounds compare at a glance Combining longevity compounds in research Because these compounds act on different hallmarks, some study designs pair them for example, a mitochondrial peptide alongside an antioxidant

It performs less well when the main issue is severe structural degeneration, uncontrolled overuse, poor sleep, inadequate protein intake, or a problem that requires procedural or surgical care

While hydroquinone was once an OTC option, the FDA has reined in the controversial benzene derivative, making it prescription-only in the United States as of September 2020

Not FDA approved for human use