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It plays a critical role in: Reducing oxidative stress Supporting the liver in detoxification Boosting immunity Regulating melanin (skin pigment) production The skin-lightening effect of glutathione comes from its ability to shift melanin production from eumelanin (dark pigment) to pheomelanin (light pigment)

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Understanding Hyperpigmentation Hyperpigmentation occurs when certain areas of the skin become darker than the surrounding areas, often caused by sun exposure, hormonal changes, or skin injuries

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Abnormalities in various metabolic pathways such as glucose 80 or amino acid metabolic system 81 in chondrocytes have been implicated in activating catabolic cascades in osteoarthritic cartilage 82