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Carlas approach also includes education around meal pacing, hydration, supportive habits, follow-up visits, and realistic maintenance planningbecause sustainable progress requires more than a prescription alone

One important finding from SURMOUNT-5: tirzepatide was actually better tolerated in this trial

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Indeed, in physiological conditions, plasma GLP-1 has been suggested to increase not only after meals, but also in the pre-ingestive, cephalic phase, with its peak observed about an hour prior to meal initiation in rats [55]

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