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Your thymosin alpha-1, I think, is always your go-to

The glucagon-like peptide-1 (GLP-1) receptor agonist drug class, used to manage type 2 diabetes, is also proving to be highly effective for the treatment of obesity and has the potential to meet this growing need

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GLP-1 RAs bypass genetic defects in the leptin-melanocortin system, promote weight loss, and improve metabolic function through the coordinated regulation of blood glucose and appetite [64,65] [Figure 2]