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As you get older, the systems that rely on NAD+ (like energy production, cognitive function, skin repair, immune health, and inflammation regulation) start to slow down, and declining NAD+ levels appear to be a key driver behind that slowdown

However it is advisable to deliver Vit B12 dose by a deep Intramuscular injection in gluteal or deltoid muscle Alternatively, you can also use oral Vitamin 12 tablets available at most health food stores and pharmacies

[1] Selectivity testing indicated the scaffold did not inhibit related SAM-dependent methyltransferases or NAD+ salvage enzymes

And while you can get it from your diet, many people still don't get enough

Cyanocobalamin Widely used in fortified foods, cyanocobalamin is a synthetic form of vitamin B12