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If insufficient, osmotic laxatives such as polyethylene glycol are generally safe and effective as first-line agents per AGA-ACG guidelines

These effects could explain why researchers are exploring whether the medicines might also benefit conditions such as depression, anxiety, bipolar disorder, and substance use disorders

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In contrast, hedonic eating refers to consuming food for its pleasurable taste and reward, rather than to meet metabolic needs (Lowe and Butryn, 2007), and does not necessarily imply loss of control or compulsive overeating

Plates were incubated at room temperature for 30-60 min in the dark, and fluorescence was read at Ex/Em = 490/520 nm