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Reduced inflammation and less scarring result from its anti-inflammatory signaling and antioxidant action, which can preserve tissue architecture important for implantation or spermatogenesis

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A number of GPCRs (McCulloch et al., 2001), including the CB1 cannabinoid receptor (Koch et al., 2006), and MOR and DOR (Koch et al., 2003, 2004, 2006), activate PLD to affect exocytosis, cytoskeletal reorganization, and cellular proliferation (Ghosh et al., 2003

PLoS ONE 11(5):e0154560 Durand ML (2017) Bacterial and fungal endophthalmitis

These detrimental effects are linked to suppression of the Nrf2 antioxidant pathway