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NAFLD Fibrosis Score (NFS)

mTOR-related brain dysfunctions in neuropsychiatric disorders

The STEP 1 trial (Wilding et al., NEJM 2021) demonstrated an average 14.9% body weight reduction with semaglutide 2.4mg weekly over 68 weeks, compared to 2.4% with placebo a magnitude of effect that no prior anti-obesity medication had achieved