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If you develop persistent diarrhea or constipation beyond the first few weeks of treatment, discuss fiber intake and meal composition with your doctor

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Many factors are involved and play a substantial role in the development of DN, which include metabolic alterations, hemodynamic disorders, and dysregulation of hormone pathways, most especially angiotensin II, which itself, contributes to renal injury via oxidative stress [4]

Cells (2022) 11(9):1413

And saying NO to extra demands put on by those around us may be the most powerful of all