doi: 10.3389/fimmu.2023.1284057 Received 27 August 2023 Accepted 11 October 2023 Published 20 October 2023 Volume 14 - 2023 Edited by Yingfeng Wan, University of Michigan, United States Reviewed by Wancun Zhang, Zhengzhou University, China
This peptide is the active ingredient in the topical copper peptides that have been sold as cosmetic agents on the dermatology shelf since the late 1980s, with the caveat being that topical GHK-Cu needs to penetrate the stratum corneum layer of skin before getting to the dermis, which houses the receptors for the peptide
By eating more foods rich in sulfur, levels of this important amino acid can be increased, thus aiding glutathione synthesis
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Regarding duration, visible skin benefits typically require consistent use for 6-12 weeks before noticeable changes occur