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L-Carnitine is an amino acid derivative that transports long-chain fatty acids into mitochondria for beta-oxidation, the cellular process that burns fat
Remarkably, in survival analysis, four upregulated genes ( OSGIN1 , RGS17 , SRXN1 , AKR1B10 ) are negative prognostic markers for TNBC
When increasing concentrations of KA were added in the presence of L-dopa as the substrate, a similar mode of mixed inhibition was observed, with K I of 3.5 M and K IS of 150 M, similar to previous studies that reported K I values of 3.4, 5 and 4.7 M for mushroom tyrosinase 18,19,33