Several trial limitations, including the small sample size, limit the interpretation of these preliminary findings, which require validation in a larger trial
The organization also questioned whether the decision to end the shortages was too soon, as it noted hundreds of thousands of patients will have to transition to the brand-name medications in just a few months
Summary: How retatrutide is dosed is based solely on Phase 2 clinical trial protocols, starting at 2 mg once weekly subcutaneously and escalating gradually to a maximum of 12 mg, as the drug remains unlicensed in the UK with no MHRA-approved dosing schedule
SAHPRA did not provide the names of the applicants or the timelines for potential approval
Swallow whole : Do not split, crush, or chew the tablet, as this affects the absorption enhancer