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Pre-Blend Reconstitution Math (70 mg total) Metric Blend composition Value 50 mg GHK-Cu + 10 mg TB-500 + 10 mg BPC-157 Metric BAC water added Value 3 mL Metric Total concentration Value 23.3 mg/mL total blend Metric Standard daily dose Value 0.10 mL (10 units) = ~2.33 mg total Component Delivery at 10 Units Compound GHK-Cu Per-Dose Amount ~1.67 mg Compound TB-500 Per-Dose Amount ~0.33 mg Compound BPC-157 Per-Dose Amount ~0.33 mg TB-500 is the limiting reconstitution-stability window most workflows use the reconstituted blend within 1-2 weeks

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Results: Significant reduction in modified MASI was observed in patients treated with topical and oral glutathione ( p =0.011) and ( p =0.007) respectively, while patients treated with topical or oral placebo had no response

FIGURE 3 3.3 GHK-Cu promoted mucosal healing GHK-Cu treatment significantly enhanced of ZO-1 and Occludin expression in colitic mice, which were downregulated by DSS (Figures 4AC)

U54HD061221), which is a part of the National Institutes of Health (NIH) Rare Disease Clinical Research Network (RDCRN), supported through collaboration between the Office of Rare Diseases Research (ORDR), the National Center for Advancing Translational Science (NCATS) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and NIH K08DK106453