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Excess adiposity contributes to hormonal imbalances, including reduced testosterone levels in men and altered estrogen metabolism in women

Ozempic, which was first designed for adults with Type 2 diabetes and to help lower blood sugar, has also been shown to reduce heart and kidney problems

Persistent vomiting or diarrhoea can lead to dehydration and potential acute kidney injury, so prompt medical review is essential if unable to maintain adequate fluid intake

In contrast, ATTR-CM, which arises from gain-of-function mutations, 260 has been the focus of all three therapeutic approaches, with multiple candidates already in clinical development (Fig

In the case of semaglutide, it is a relatively new drug for managing type 2 diabetes and for weight loss, so scientists are still studying its full range of side effects, including those that may affect urination