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A long-acting once-weekly agonist does not reach its steady-state blood level after a single injection it accumulates over several doses until intake and clearance balance

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(2023) demonstrated that moderate Drp1 upregulation in ALS Drosophila models restores physiological mitochondrial distribution within axons, enabling efficient mitochondrial trafficking to nerve terminals and thereby meeting axonal energy demands

I am so incredibly excited about the conversation that I am about to have

Lake JE (2021)