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PTR (2001) 15:3914

50 In any emergency contraceptive, efficacy decreases as the time between intercourse and treatment increases

After exposure to electrophilic or oxidative stress, the sensor residues cysteine of Keap1, especially C151, C226, C273, and C288, undergo oxidation and modification, causing conformational changes that inhibit Keap1-mediated NRF2 degradation [94]

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