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Animal models for type 1 and type 2 diabetes: advantages and limitations

Burk RF, Hill KE, Motley AK et al (2006) Deletion of selenoprotein P upregulates urinary selenium excretion and depresses whole-body selenium content

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Furthermore, for specific compounds, additional key mechanisms such as Fas-mediated signal transduction, loss of cellular redox homeostasis, ATP depletion, changes in ion channels, and activation of kinases and caspases, among others, have been highlighted