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CD8 + T cells of the knockout mice were intrinsically defective in balancing homeostasis in the peripheral environment, implicating GPX4 is required for T cell-regulated immune responses (Matsushita et al., 2015)

Acknowledgments We would like to acknowledge the financial support from the Ministry of Education in the Long Term Research Grant Scheme (LRGS/BU/2012/UKM-UKM/K/01) and also the direct and indirect input from the research team toward the study

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Rose S, Frye RE, Slattery JC, Wynne R, Tippett M, Melnyk S, James SJ (2015) Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines

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