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Pantothenic acid, riboflavin, choline, chromium, iodine, magnesium, selenium, and vanadium either have no established effectiveness ratings in our data or show insufficient evidence for most claimed uses

The missing pieces are big: no human dosing, no human pharmacokinetics, no controlled human safety data, and no long-term outcome data in any species

And interestingly, the valuations are quite good, both on an absolute as well as on a relative basis

Int J Dev Neurosci 55:4148 Zhang K, Lin W, Zhang J, Zhao Y, Wang X, Zhao M (2020) Effect of Toll-like receptor 4 on depressive-like behaviors induced by chronic social defeat stress

106 ZhuM.SunY.SuY.GuanW.WangY.HanJ.et al (2024)