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This makes them more effective than traditional appetite suppressants that rely on stimulatory pathways

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VerbalisJGGoldsmithSRGreenbergAKorzeliusCSchrierRWSternsRHet al

This is characterized by the accumulation of low-density lipoprotein within the artery walls, leading to the formation of atheroma and distinct plaques consisting of proliferative fibrous tissue and calcifications (109, 110)

Evidence shows that stopping usually leads to rapid weight regain and loss of cardiometabolic benefits, suggesting these medications must be used long term to maintain health gains