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A newer medication, Tirzepatide, also addresses type 2 diabetes and obesity but offers a dual-action approach by combining GLP-1 receptor agonism with GIP activation

Compounding pharmacies have partially addressed this gap, but they too face regulatory uncertainty as the FDA navigates the complex legal landscape around peptide regulation

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Most BPC-157 and TB-500 data is preclinical

Abstract Purpose of Review The aim of this review is to provide a comprehensive summary of current clinical evidence on the relationship between GLP-1 receptor agonists and pediatric obesity, to evaluate these findings from metabolic and therapeutic perspectives, and to offer potential directions for future research in the field