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The label notes, In Zepbound clinical trials, hair loss was reported more frequently in female than male patients in the Zepbound (7.1% female versus 0.5% male) and placebo (1.3% female versus 0% male) treatment groups. Treatments for hair loss Experts say telogen effluvium with GLP-1 use is typically temporary, but people who develop hair loss should seek medical evaluation

Lawrence ECN, et al

Together, we will design a glide path that includes: Deciding whether to continue on a lower maintenance dose, taper off, or pause with a clear restart plan

While uncommon, these serious adverse events require ongoing monitoring and risk assessment, particularly with long-term therapy

Because it affects three signaling pathways simultaneously, it enables investigation of receptor cross-talk and synergistic mechanisms that were difficult to study with single or dual-target compounds