Anti-Apoptotic HDL HDL have multiple anti-apoptotic properties that enhance cell survival (Figure 10)
Patients should be counselled on recognising hypoglycaemic symptoms such as sweating, tremor, confusion, or palpitations
What sets tirzepatide apart is that it is a first-in-class dual agonist: it activates two gut-hormone receptors at once (GIP and GLP-1), whereas semaglutide targets GLP-1 alone
Duration of therapeutic effects : The effects typically last for 2-4 hours, making it ideal for short-term use
Further analyses revealed that cotadutide 300 g improved lipid profiles, liver enzyme levels (AST and ALT), and markers of liver fibrosis, including propeptide of type III collagen, and fibrosis-4 index, compared to placebo