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Week 24: Add GHK-Cu (daily or 5x/week, subcutaneous)

B.RasicZ.SeverM.DrmicD.et al (2016)

10.3390/biomedicines9050526 [DOI] [PMC free article] [PubMed] [Google Scholar] Raghunandan M, Yeo JE, Walter R, Saito K, Harvey AJ, Ittershagen S, Lee E, Yang J, Hoatlin ME, Bielinsky AK, Hendrickson EA, Schrer O, Sobeck A (2020) Functional cross talk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery

Although the mechanism(s) underlying NASH progression remain to be fully elucidated, accumulating evidence suggests that both oxidative stress and the pro-inflammatory cytokine tumor necrosis factor- (TNF) are critical contributors in this process 5

Although BPTES and V-9302 treatment can promote M1 macrophage polarization or enhance CD8 + T cell anti-tumor function, they have also been found to enhance the expression of PD-L1 on tumor cells (Liu et al., 2017