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We generally advise against pre-loading syringes for extended periods

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FIGURE 1 In the same arena of fetal Hb induction, another successful approach is the recent FDA approval of gene therapy crisper-cas9 gene editing (Casgevy) (Figure 1)

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Search strategy A systematic review of the available literature was performed according to the PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines for the conduct of systematic reviews of intervention studies [9]