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Celecoxib alleviates the dss-induced ulcerative colitis in mice by enhancing intestinal barrier function, inhibiting ferroptosis and suppressing apoptosis

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A recent in vitro study showed that PINK1-dependent phosphorylation of Ser111 of Rab8A antagonistically regulates the phosphorylation of Thr72 of Rab8A by LRRK2 (Vieweg et al., 2020), suggesting that there might be even closer crosstalk between the two master kinase