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The molecule is too large to cross the lining of the mouth without specialized formulation, and the only published study to test the question, in beagle dogs, found minimal absorption
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Metformin for prevention of hypertensive disorders of pregnancy in women with gestational diabetes or obesity: systematic review and meta-analysis of randomized trials
GLP-1 medications come with real costs and side effects, and the risk-benefit math does not support their use as a primary cancer prevention strategy
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