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These changes are harmless and should not affect the efficacy of the product

Excess NADH (and concomitant NAD depletion) directly impairs this NAD-dependent step, causing a buildup of upstream glycolytic intermediates and a block in downstream flux 112,113

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In September 2023, the FDA added BPC-157 to its Category 2 list of bulk drug substances under its Interim Policy on Compounding, meaning 503A compounding pharmacies and 503B outsourcing facilities are barred from using it in compounded preparations

No cases of hypoglycemia or pancreatitis were reported in either arm