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However, N-terminal modifications, such as N-acetylation, D-norleucine substitution, or replacement with -aminobutyric acid (GABA), dramatically elongated the peptides half-lives
Polyphenols stimulate AMP-Activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
Alternative splicing, in particular, allows the production of multiple mRNA isoforms from a single pre-mRNA, thereby increasing transcriptome and proteome diversity 1416
Scientific Background Small-molecule metabolic regulators are widely used in research exploring enzymatic signaling pathways
For instance, traditional IGF-1 has a shorter half-life, which may limit its effectiveness in promoting sustained muscle growth and recovery
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