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For satisfaction signals, it directly acts on the peripheral tissues and central nervous system (CNS) and is therefore known as the satiety hormone. The obese (ob) gene encodes leptin, which is released by adipose tissue

By influencing neuromuscular control, GLP-1 receptor agonists could help prevent the collapse of the upper airway during sleep, thereby reducing the frequency and severity of apneas and hypopneas [29]

Define success metrics: Establish clear parameters for adequate response (e.g., referencing manufacturer-approved response benchmarks from the approved products prescribing information) and criteria for continuing or discontinuing therapy

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So, well go from there