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376,377,378 In a dexamethasone-induced muscle atrophy model, Ex-4 ameliorated muscle atrophy by inhibiting muscle atrophy factor and enhancing myogenic factors (MyoG and MyoD), thereby increasing muscle mass and function

The inflammasome reporter macrophage stably transduced with constructs for the expression of mCerulean-tagged ASC has been described previously 98

Human data: Human evidence is limited to a single published Phase I/II pharmacokinetic-pharmacodynamic dose-escalation study in healthy adults

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