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Gpx activity evaluation To assess Gpx (glutathione peroxidase) activity in the liver homogenates, glutathione reductase (GR), reduced glutathione (GSH), and tert-butyl hydroperoxide (tBuOOH) were added to the reaction mixture

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L-glutathione, the primary skin-brightening active, shifts melanin production from eumelanin (brown-black pigmentation) toward pheomelanin (lighter pigmentation) by reducing the oxidative environment required for eumelanin synthesis and by inhibiting tyrosinase the rate-limiting enzyme in the melanogenesis pathway

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Studies indicate it stimulates the release of growth hormone with a high degree of specificity, minimizing impact on cortisol or prolactin levels