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doi: 10.1038/nm.2207 99 WhittleAJCarobbioSMartinsLSlawikMHondaresEVzquezMJet al

H 2 S promotes the differentiation of preadipocytes into adipocytes by activating a series of transcription factors, including peroxisome proliferator-activated receptor gamma (PPAR-), CCAAT/enhancer-binding protein alpha (C/EBP), sterol regulatory element-binding protein 1 (SREBP1), and carbohydrate response element-binding protein (ChREBP), thereby increasing triglyceride accumulation

But certain groups are at higher risk: Age: Bone density naturally declines with age, especially after menopause

The presence of rim enhancement on contrast-enhanced MRI may be the only clue for the diagnosis

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