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Published head-to-head research data consistently shows Tirzepatide producing larger body composition effects than Semaglutide at comparable timepoints, at the doses studied

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Retatrutide Adds Real Value For: Tirzepatide plateau patients with significant remaining goals: If you've been on tirzepatide at maximum tolerated dose for 6+ months, your weight loss has stalled, and you still have 1525%+ of your target weight to lose, retatrutide's additional mechanism represents a genuine pharmacological step up

After two years (120 weeks), the patients retained roughly one-third of their original weight loss (5.6% of the original 17.3% loss)

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